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  • Comparative safety and immunogenicity of an

    1996-12-1 · A diphtheria and tetanus toxoid two-component acellular pertussis vaccine (DTaP), consisting of 25 μg glutaraldehyde-detoxified pertussis toxin (PT) and 25 μg native filamentous hemagglutinin (FHA), was compared with diphtheria and tetanus toxoid whole-cell pertussis vaccine (DTwP) in a randomized, double-blind manner in 286 Senegalese infants inoculated at two, four, and …

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  • Leishmania tropica (Wright) Luhe ATCC ® PRA-418™

    Leishmania tropica (Wright) ... Mix the cell preparation and the DMSO solution in equal portions. The final concentration will be 10 7 cells/mL and 5% (v/v) DMSO. The time from the mixing of the cell preparation and DMSO stock solution before the freezing process is begun should be no less than 15 min and no more than 30 min.

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  • Malaria Vaccines: Recent Advances and New Horizons:

    Development of highly effective vaccines against human malaria remains a public health priority. In this Review, Draper et al. describe the latest vaccine approaches to prevent malaria alongside immunological and molecular mechanisms of protection. Rational antigen selection, immunogen design, and novel immunization strategies offer promise for achieving high-level protection.

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  • The discovery of resistance to malaria of sickle‐cell ...

    2006-11-3 · Restriction endonuclease digests of the β-globin gene cluster show five distinct patterns associated with the sickle-cell mutation, four being observed in Africa, the Bantu, Benin, Senegal, and Cameroon types , and the fifth in the Indian subcontinent and Arabia . This is evidence that the HbS mutation occurred independently at least five times.

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  • Priapism in Sickle Cell Disease: An Evaluation of the ...

    2021-6-1 · In a cross-sectional study consisting of 114 Nigerian patients with homozygous sickle cell disease, only 21% were knowledgeable about priapism and 67.5% of them were not aware of the risk of priapism in sickle cell disease. 8 Similar findings were seen in a study of patients in Senegal wherein of 108 patients with sickle cell anemia, 10.2% knew ...

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  • Safety and Immunogenicity of a Heterologous Prime

    Background: The 2014 West African outbreak of Ebola virus disease highlighted the urgent need to develop an effective Ebola vaccine. Methods: We undertook 2 phase 1 studies assessing safety and immunogenicity of the viral vector modified vaccinia Ankara virus vectored Ebola Zaire vaccine (MVA-EBO-Z), manufactured rapidly on a new duck cell line either alone or in a heterologous prime-boost ...

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  • Mature T‐ and NK‐cell non‐Hodgkin lymphoma in

    2016-3-15 · The genetic basis of T/NK cell lymphomas in children and young adolescents remains largely unknown. Anthracycline‐based regimens and haematopoietic stem cell transplants (allogeneic and autologous) are current treatment modalities, however it is anticipated that novel targeted therapeutic agents will be available in the near future.

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  • E. coli Positive Control (Escherichia coli ) Whole Cell ...

    2012-11-27 · E. coli Positive Control (Escherichia coli ) Whole Cell Lysate - expressing 6X His tag protein validated for WB. The cell lysate was prepared from E.coli (Tuner [De3]) expressing a 14.2 kDa protein…

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  • Medicago sativa - an overview | ScienceDirect Topics

    2010-6-4 · E. Sedaghati, H Hokmabadi, in Encyclopedia of Food Safety, 2014 Risk of Pollen Migration in Transgenic Alfalfa. Alfalfa (Medicago sativa L.) is a perennial legume widely cultivated to provide high-quality forage in the form of hay, silage, and to a lesser extent as a grazing crop, as well as for improving soil fertility.The availability of alfalfa lines that can be easily transformed with ...

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  • Study of Efficiencies CdTe/CdS Photovoltaic Solar Cell ...

    The photovoltaic performance (efficiency η) of an ITO/CdS/CdTe structure cell is studied in this article according to its electrical properties. The study is carried out by simulation with SCAPS (Solar Cell Capacitance Simulator) whose mathematical model is based on solving the equations of Poisson and continuity of electrons and holes. An electrical conversion efficiency of 23.58% is ...

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  • Leishmania tropica (Wright) Luhe ATCC ® PRA-418™

    Leishmania tropica (Wright) ... Mix the cell preparation and the DMSO solution in equal portions. The final concentration will be 10 7 cells/mL and 5% (v/v) DMSO. The time from the mixing of the cell preparation and DMSO stock solution before the freezing process is begun should be no less than 15 min and no more than 30 min.

    Get Price
  • Wireless Compression Load Cell - LoadSafe - Crosby ...

    2021-6-3 · LoadSafe - Wireless Compression Load Cell is taking the heavy lift and structural weighing industry by storm. By adding the Straightpoint wireless system to the already popular compression load cell line we have developed a cost-effective alternative to standard compression load cells.

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  • Safety and Immunogenicity of a Heterologous Prime

    Background: The 2014 West African outbreak of Ebola virus disease highlighted the urgent need to develop an effective Ebola vaccine. Methods: We undertook 2 phase 1 studies assessing safety and immunogenicity of the viral vector modified vaccinia Ankara virus vectored Ebola Zaire vaccine (MVA-EBO-Z), manufactured rapidly on a new duck cell line either alone or in a heterologous prime-boost ...

    Get Price
  • Human Recombinant EGF | STEMCELL Technologies

    The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is 0.1 ng/mL. (B) 2 μg of Human Recombinant EGF was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining.

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  • Novel viral vectors in infectious diseases - Humphreys ...

    This unique induction of CD8 + T‐cell responses was attributed to deletion of the Rh157.5/4 genes within the fibroblast‐adapted RhCMV vector. 32 Rh157.5/4 are orthologues of the HCMV UL128/UL130 genes that encode components of the viral pentameric complex that is required for viral entry into non‐fibroblast cells. 33 How deletion of these ...

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  • E. coli Positive Control (Escherichia coli ) Whole Cell ...

    2015-5-1 · Live attenuated vaccines against human viral diseases have been amongst the most successful cost effective interventions in medical history. Smallpox was declared eradicated in 1980; poliomyelitis is nearing global eradication and measles has been controlled in most parts of the world.

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  • Live attenuated vaccines: Historical successes and

    2020-8-12 · Sickle cell disease (SCD) is a group of blood disorders caused by mutations in HBB that promote polymerization of hemoglobin and sickling of erythrocytes. The most common and most clinically severe form of SCD is sickle cell anemia (SCA [MIM: 603903]) and is caused by homozygosity of the sickle mutation HbS.

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  • Genetic modifiers of long‐term survival in sickle cell ...

    2020-8-21 · Gut bacteria are involved in the education of T cell immune responses, and the intestinal ecosystem influences anticancer immunity. Fluckiger et al. report microbial antigens that might cross-react with antigens associated with tumor cells. They found that a type of intestinal bacteria called enterococci harbor a bacteriophage that modulates immune responses.

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  • Advancing Cell Biology with Cryo-Correlative

    2021-1-28 · Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging modalities to study systems in 4D. Combining fluorescence microscopy with cryo-electron tomography allows investigators to bridge knowledge gaps between cell and structural biology. CLEM technologies are rapidly advancing in order to improve biological …

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  • Wireless Compression Load Cell - LoadSafe - Crosby ...

    2021-6-3 · LoadSafe - Wireless Compression Load Cell is taking the heavy lift and structural weighing industry by storm. By adding the Straightpoint wireless system to the already popular compression load cell line we have developed a cost-effective alternative to standard compression load cells.

    Get Price
  • Human Recombinant EGF | STEMCELL Technologies

    The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is 0.1 ng/mL. (B) 2 μg of Human Recombinant EGF was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining.

    Get Price
  • Novel viral vectors in infectious diseases - Humphreys ...

    This unique induction of CD8 + T‐cell responses was attributed to deletion of the Rh157.5/4 genes within the fibroblast‐adapted RhCMV vector. 32 Rh157.5/4 are orthologues of the HCMV UL128/UL130 genes that encode components of the viral pentameric complex that is required for viral entry into non‐fibroblast cells. 33 How deletion of these ...

    Get Price
  • COS-7 | ATCC

    This line contains T antigen, retains complete permissiveness for lytic growth of SV40, supports the replication of ts A209 virus at 40°C, and supports the replication of pure populations of SV40 mutants with deletions in the early region. The line was derived from the CV-1 cell line (ATCC CCL-70 ) by transformation with an origin defective mutant of SV40 which codes for wild type T antigen.

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  • The early landscape of coronavirus disease 2019

    2020-5-27 · The resulting immunity can be mediated by humoral antibody induction, and/or cellular T-cell effector function. Spike glycoprotein (S) is the sole surface protein of the SARS-CoV-2 virion. 18 SARS-CoV-2 S mediates viral entry into host cells via angiotensin-converting enzyme 2, which is expressed at high levels on the surface of pulmonary ...

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  • Cross-reactivity between tumor MHC class I–restricted ...

    2020-8-21 · Gut bacteria are involved in the education of T cell immune responses, and the intestinal ecosystem influences anticancer immunity. Fluckiger et al. report microbial antigens that might cross-react with antigens associated with tumor cells. They found that a type of intestinal bacteria called enterococci harbor a bacteriophage that modulates immune responses.

    Get Price
  • Detection of Hypermethylated Genes in Women with

    Chen et al. ( 34) detected hypermethylation of E-cadherin (CDH1) in all five cell lines examined and 8 of 20 tumor samples. Hypermethylation of RASSF1A (RASSF1) was detected in 11 of 33 squamous cell cancers and none of 11 normal control samples ( 36) . Tripathi et al. ( 37) detected hypermethylation of p16 (CDKN2A) in 3 of 46 cervical lesions.

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  • Cervical cancer: A global health crisis - Small - 2017 ...

    2017-5-2 · INTRODUCTION. Cervical cancer is one of the leading causes of cancer death among women. 1 Worldwide, cervical cancer is the fourth most frequently occurring malignancy in women, and results in an estimated 530,000 new cases annually with 270,000 deaths. Approximately 85% of the worldwide deaths from cervical cancer occur in underdeveloped or developing countries, and the …

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  • Antibodies to watch in 2021

    Introduction. Each year since 2010, the ‘Antibodies to Watch’ articles have faithfully reported key events related to antibody therapeutics in late-stage development and regulatory review, and those that were recently approved. 1–13 Events that occurred during 2020, however, were unprecedented due to coronavirus disease 2019 (COVID-19). During January – November 2020, over 60 million ...

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  • Wireless Compression Load Cell - LoadSafe - Crosby ...

    2021-6-3 · LoadSafe - Wireless Compression Load Cell is taking the heavy lift and structural weighing industry by storm. By adding the Straightpoint wireless system to the already popular compression load cell line we have developed a cost-effective alternative to standard compression load cells.

    Get Price
  • Lg wright | Etsy

    Check out our lg wright selection for the very best in unique or custom, handmade pieces from our cell phone accessories shops.

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  • Human Recombinant EGF | STEMCELL Technologies

    The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is 0.1 ng/mL. (B) 2 μg of Human Recombinant EGF was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining.

    Get Price
  • EpiCult™-B Mouse Mammary Epithelial Cell Medium

    Unlike human mammary CFC colonies, subtypes of mouse mammary epithelial cell colonies are not easily identifiable. All colonies were cultured in either EpiCult®-B (Human: Catalog #05601) or EpiCult®-B (Mouse:Catalog #5610) in the presence of an irradiated NIH 3T3 feeder layer. Colonies were visualized by staining with Wright's Giemsa.

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  • Frontiers | Polymorphisms in Inflammatory Genes

    2020-9-4 · Sickle cell disease (SCD), the most common monogenic disease worldwide, is marked by a phenotypic variability that is, to date, only partially understood. Because inflammation plays a major role in SCD pathophysiology, we hypothesized that single nucleotide polymorphisms (SNP) in genes encoding functionally important inflammatory proteins might modulate the occurrence of SCD complications.

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  • Population structure and diversity of Plasmodium ...

    2021-5-13 · Genetic diversity in Plasmodium falciparum populations can be used to describe the resilience and spatial distribution of the parasite in the midst of intensified intervention efforts. This study used microsatellite analysis to evaluate the genetic diversity and population dynamics of P. falciparum parasites circulating in three ecological zones of Ghana.

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  • Farming the planet: 2. Geographic distribution of crop ...

    1. Introduction [2] Human land uses practices, especially those tied to agriculture, have transformed the biosphere [Vitousek et al., 1997a; Foley et al., 2005].The ∼40% of terrestrial photosynthesis appropriated for human use [Haberl et al., 2007; Vitousek et al., 1986; Rojstaczer et al., 2001], the ∼50% of the global nitrogen flux from synthetic fertilizers and fossil fuels combustion ...

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